What is Stereology.info?
The Most Comprehensive Source of Stereology Information on the Web
Stereology.info, the Stereology Information Center, includes a wide range of knowledge about stereology. This site introduces both basic and advanced concepts in the field. The emphasis is on its use in biological research, though anyone interested in learning concepts of stereology will find something of interest. The application of stereological methods to biological studies permits researchers to effectively and efficiently gather data. This site is dedicated to helping researchers understand the principles of design-based stereology and its advantages over less sophisticated approaches in quantitative histology.
Design-based stereology is a set of methods to ensure rigorous quantitative analysis of the size, shape, and number of objects. When properly used, stereology plays an important role in validating and rejecting experimental hypotheses in biological research. It produces results that are unbiased, efficient, and more reliable than other ad hoc quantitative analyses. Unbiased stereology provides an important contribution to the advancement in biological research by improving the consistency and dependability of quantitative analytical results produced in the laboratory and reported in scientific publications.
Recent Noteworthy Stereology Publications
Published papers using Stereology; last updated on 03/06/2013, * indicates an example where a good job was done reporting stereological parameters
Acute exercise prevents the development of neuropathic pain and the sprouting of non-peptidergic (GDNF- and artemin-responsive) c-fibers after spinal cord injury
Synergistic and additive effects of enriched environment and lithium on the generation of new cells in adult mouse hippocampus
Intermittent fasting attenuates increases in neurogenesis after ischemia and reperfusion and improves recovery
Non-serine-phosphorylated tyrosine hydroxylase expressing neurons are present in mouse striatum, accumbens and cortex that increase in number following dopaminergic denervation
Immunological ignorance allows long-term gene expression following perinatal rAAV-mediated gene transfer to murine airways
The recovery of acetylcholinesterase activity and the progression of neuropathological and pathophysiological alterations in the rat basolateral amygdala after soman-induced status epilepticus: Relation to anxiety-like behavior
Recommended Stereology Workshops and Courses
Organized by Professor Mark West
March 15-20, 2014
Marine Biological Laboratory
Woods Hole, MA (USA)
The goal of the workshop is to teach a small group of research scientists how to design, supervise, and critically evaluate stereological studies of the nervous system. Stereology is a methodology that provides meaningful quantitative descriptions of the geometry of three-dimensional structures from measurements that are made on two-dimensional images sampled from a structure of interest. The workshop will emphasize modern ”design based” stereology, which is characterized by the preparation and probing of tissue in such a manner that no assumptions about the size, shape, and orientation of the structures being quantified are necessary.
The target audience includes neuroscience research scientists working at the graduate student, post-doctoral, and senior scientists who are interested in the practical application of design based stereological methods. The number of participants will be limited to 30, to ensure robust faculty-student interaction.
Organized by Dr. Daniel Peterson
August 18-22, 2014
Chicago, IL (USA)
The purpose of this intensive, week-long workshop is to provide a comprehensive background in the theory and practice of modern histological preparation and microscopic analysis for researchers in biomedical science. The workshop provides a practical tutorial in all aspects of microscopic analysis including experimental design, specimen preparation, use of fluorescence and confocal microscopes, design-based stereology, and image preparation for scientific publication. A variety of microscopes equipped for stereology are available for use. Participants should bring examples of their material and problems for discussion. In addition to lectures, substantial time is devoted to “hands-on” practical sessions. Attendees participate in group discussion, where they can discuss their research applications and consult with the instructors.
Note: MBF has a policy of not promoting courses that are taught by commercially affiliated instructors. There are other stereology courses that are offered by organizations that use instructors with direct commercial interests in the products that are demonstrated during these courses. If you have a doubt, ask the instructor directly if they have a commercial affiliation with the products demonstrated at their course. Contact MBF if you have any questions about courses not listed here or about our policy.